As for profiles, the epson ones are, from the posts I've seen, excellent - no need for custom ones if you stick to epson papers and inks.
this is exactely the point where it comes to costs!
I've compared roll paper EPSON with roll paper HP and equvalent papers @ EPSON are 2x till 3x more expensive. The HahnenmÃ¼hle are even more expensive.
Of course not everyboday prints huge amounts but if costs matter I'd suggest to think also about a completely different solution e.g. the DesignJet 90 - you get for roughly 1 k EUR the printer and for sure the lowest possibel running costs at the same quality level and also > 85 years on the Premium Plus papers from HP. If you then use rollpaper + 3ink packs from HP the costs should be roughly 1/3 cheaper compare to the 4800 EPSON.
If you're not intending to produce huge amounts of prints the running costs should not affect your decition - I'd wait for test results or agree to kev and get the 2400 from EPSON - for sure an excellent printer but for sure in the long run more expensive than a HP DesignJet 90 where the runnings costs are approcimately only 1/3 of the costs of a normal HP prosumer printer.
HP states that the midrange printers are for low throughput @ reasonable costs and the pro printers (DesignJet family) are for high thoughput at reasonable costs. It's always all about the typical use case.
I'd only get a 2400 EPSON if I'd mianly print on very expensiev Fine Art paper (a very valid reason I think)
The running costs of my HP DJ 130 (with exceptional printing quality) are much lower than previously of my EPSON Stylus Photo 900.
One last remark to ICC profiles - I'd always try to get tailor made ones because I love to try out different papers (also due to lower printing costs)
Just have also a look here - and you'll get an impression what tailor made profiles do to the EPSON 2400: http://www.camerahobby.com/Digital_PrintFIX_PRO.htm
(first with EPSON profiles and 2nd with tailr made ones